CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.10 | Jelly Rolls |
Domain Context
CATH Clusters
| Superfamily | Jelly Rolls |
| Functional Family | dTDP-4-dehydrorhamnose 3,5-epimerase |
Enzyme Information
| 5.1.3.13 |
dTDP-4-dehydrorhamnose 3,5-epimerase.
based on mapping to UniProt P9WH11
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose.
-!- Occurs in a complex with EC 1.1.1.133.
|
UniProtKB Entries (1)
| P9WH11 |
RMLC_MYCTU
Mycobacterium tuberculosis H37Rv
DTDP-4-dehydrorhamnose 3,5-epimerase
|
PDB Structure
| PDB | 1PM7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis.
Bioorg.Med.Chem.Lett.
|
