CATH Classification

Domain Context

CATH Clusters

Superfamily PLAT/LH2 domain
Functional Family Triacylglycerol lipase

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt P00591
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (1)

P02703
COL_PIG
Sus scrofa
Colipase

PDB Structure

PDB 1ETH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Lipase activation by nonionic detergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether complex.
Hermoso, J., Pignol, D., Kerfelec, B., Crenon, I., Chapus, C., Fontecilla-Camps, J.C.
J.Biol.Chem.
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