CATH Classification

Domain Context

CATH Clusters

Superfamily DNA-3-methyladenine glycosylase AlkA, N-terminal domain
Functional Family DNA-3-methyladenine glycosylase 2

Enzyme Information

3.2.2.21
DNA-3-methyladenine glycosylase II.
based on mapping to UniProt P04395
Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.

UniProtKB Entries (1)

P04395
3MG2_ECOLI
Escherichia coli K-12
DNA-3-methyladenine glycosylase 2

PDB Structure

PDB 1DIZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA.
Hollis, T., Ichikawa, Y., Ellenberger, T.
EMBO J.
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