CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1150 | Aspartate Aminotransferase, domain 1 |
|
3.90.1150.10 | Aspartate Aminotransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aspartate Aminotransferase, domain 1 |
| Functional Family |
Enzyme Information
| 2.6.1.5 |
Tyrosine transaminase.
based on mapping to UniProt P33447
L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.
-!- L-phenylalanine can act instead of L-tyrosine. -!- The mitochondrial enzyme may be identical with EC 2.6.1.1. -!- The three isoenzymic forms are interconverted by EC 3.4.22.32 and EC 3.4.22.33. -!- The enzyme can also catalyze the final step in the methionine-salvage pathway of Klebsiella pneumoniae.
|
UniProtKB Entries (1)
| P33447 |
ATTY_TRYCR
Trypanosoma cruzi
Tyrosine aminotransferase
|
PDB Structure
| PDB | 1BW0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode.
Protein Sci.
|
