# STOCKHOLM 1.0
#=GF ID 3.40.50.720/FF/57388
#=GF DE 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase
#=GF AC 3.40.50.720/FF/57388
#=GF TP FunFam
#=GF DR CATH: 4.2
#=GF DR DOPS: 1.857
#=GS 1hdcA00/1-254     AC P19992
#=GS 1hdcA00/1-254     OS Streptomyces exfoliatus
#=GS 1hdcA00/1-254     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 1hdcA00/1-254     DR CATH; 1hdc; A:2-255; 
#=GS 1hdcA00/1-254     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 1hdcA00/1-254     DR EC; 1.1.1.53; 
#=GS 1hdcB00/1-254     AC P19992
#=GS 1hdcB00/1-254     OS Streptomyces exfoliatus
#=GS 1hdcB00/1-254     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 1hdcB00/1-254     DR CATH; 1hdc; B:2-255; 
#=GS 1hdcB00/1-254     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 1hdcB00/1-254     DR EC; 1.1.1.53; 
#=GS 1hdcC00/1-254     AC P19992
#=GS 1hdcC00/1-254     OS Streptomyces exfoliatus
#=GS 1hdcC00/1-254     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 1hdcC00/1-254     DR CATH; 1hdc; C:2-255; 
#=GS 1hdcC00/1-254     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 1hdcC00/1-254     DR EC; 1.1.1.53; 
#=GS 1hdcD00/1-254     AC P19992
#=GS 1hdcD00/1-254     OS Streptomyces exfoliatus
#=GS 1hdcD00/1-254     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 1hdcD00/1-254     DR CATH; 1hdc; D:2-255; 
#=GS 1hdcD00/1-254     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 1hdcD00/1-254     DR EC; 1.1.1.53; 
#=GS 2hsdA00/1-253     AC P19992
#=GS 2hsdA00/1-253     OS Streptomyces exfoliatus
#=GS 2hsdA00/1-253     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 2hsdA00/1-253     DR CATH; 2hsd; A:2-255; 
#=GS 2hsdA00/1-253     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 2hsdA00/1-253     DR EC; 1.1.1.53; 
#=GS 2hsdB00/1-253     AC P19992
#=GS 2hsdB00/1-253     OS Streptomyces exfoliatus
#=GS 2hsdB00/1-253     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 2hsdB00/1-253     DR CATH; 2hsd; B:2-255; 
#=GS 2hsdB00/1-253     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 2hsdB00/1-253     DR EC; 1.1.1.53; 
#=GS 2hsdC00/1-253     AC P19992
#=GS 2hsdC00/1-253     OS Streptomyces exfoliatus
#=GS 2hsdC00/1-253     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 2hsdC00/1-253     DR CATH; 2hsd; C:2-255; 
#=GS 2hsdC00/1-253     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 2hsdC00/1-253     DR EC; 1.1.1.53; 
#=GS 2hsdD00/1-253     AC P19992
#=GS 2hsdD00/1-253     OS Streptomyces exfoliatus
#=GS 2hsdD00/1-253     DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS 2hsdD00/1-253     DR CATH; 2hsd; D:2-255; 
#=GS 2hsdD00/1-253     DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS 2hsdD00/1-253     DR EC; 1.1.1.53; 
#=GS P19992/2-255      AC P19992
#=GS P19992/2-255      OS Streptomyces exfoliatus
#=GS P19992/2-255      DE 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
#=GS P19992/2-255      DR GENE3D; 4b8839834402d5665fa5a9a7559bef95/2-255; 
#=GS P19992/2-255      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces exfoliatus; 
#=GS P19992/2-255      DR EC; 1.1.1.53; 
#=GS K1UWH2/2-254      AC K1UWH2
#=GS K1UWH2/2-254      OS Streptomyces sp. SM8
#=GS K1UWH2/2-254      DE Uncharacterized protein
#=GS K1UWH2/2-254      DR GENE3D; ef486aea70857dedfb4df781e7538fac/2-254; 
#=GS K1UWH2/2-254      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. SM8; 
#=GS K1UWH2/2-254      DR EC; 1.1.1.53; 
#=GS A0A0S1UVV5/2-254  AC A0A0S1UVV5
#=GS A0A0S1UVV5/2-254  OS Streptomyces sp. FR-008
#=GS A0A0S1UVV5/2-254  DE 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase
#=GS A0A0S1UVV5/2-254  DR GENE3D; ef486aea70857dedfb4df781e7538fac/2-254; 
#=GS A0A0S1UVV5/2-254  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. FR-008; 
#=GS A0A0S1UVV5/2-254  DR EC; 1.1.1.53; 
#=GS A0A1C4MPN6/2-254  AC A0A1C4MPN6
#=GS A0A1C4MPN6/2-254  OS Streptomyces sp. BvitLS-983
#=GS A0A1C4MPN6/2-254  DE 3alpha(Or 20beta)-hydroxysteroid dehydrogenase
#=GS A0A1C4MPN6/2-254  DR GENE3D; ef486aea70857dedfb4df781e7538fac/2-254; 
#=GS A0A1C4MPN6/2-254  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. BvitLS-983; 
#=GS A0A1C4MPN6/2-254  DR EC; 1.1.1.53; 
#=GS D6BAH8/2-254      AC D6BAH8
#=GS D6BAH8/2-254      OS Streptomyces albus J1074
#=GS D6BAH8/2-254      DE 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase
#=GS D6BAH8/2-254      DR GENE3D; ef486aea70857dedfb4df781e7538fac/2-254; 
#=GS D6BAH8/2-254      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albus group; Streptomyces albus; 
#=GS D6BAH8/2-254      DR EC; 1.1.1.53; 
#=GS A0A0X3X9L1/2-254  AC A0A0X3X9L1
#=GS A0A0X3X9L1/2-254  OS Streptomyces griseus subsp. griseus
#=GS A0A0X3X9L1/2-254  DE 3-alpha-hydroxysteroid dehydrogenase
#=GS A0A0X3X9L1/2-254  DR GENE3D; ef486aea70857dedfb4df781e7538fac/2-254; 
#=GS A0A0X3X9L1/2-254  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces griseus group; Streptomyces griseus; Streptomyces griseus subsp. griseus; 
#=GS A0A0X3X9L1/2-254  DR EC; 1.1.1.53; 
#=GF TC 581.0 1.2E-179
#=GF SQ 14
1hdcA00/1-254             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVGNEPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
1hdcB00/1-254             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVGNEPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
1hdcC00/1-254             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVGNEPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
1hdcD00/1-254             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVGNEPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
2hsdA00/1-253             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
2hsdB00/1-253             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
2hsdC00/1-253             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
2hsdD00/1-253             NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
P19992/2-255              NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVGNEPGEIAGAVVKLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
K1UWH2/2-254              NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIGMKTVIPAMKEAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVFLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
A0A0S1UVV5/2-254          NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIGMKTVIPAMKEAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVFLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
A0A1C4MPN6/2-254          NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIGMKTVIPAMKEAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVFLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
D6BAH8/2-254              NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIGMKTVIPAMKEAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVFLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
A0A0X3X9L1/2-254          NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIGMKTVIPAMKEAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNTPMGRVG-EPGEIAGAVVFLLSDTSSYVTGAELAVDGGWTTGPTVKYVMGQ
#=GC scorecons            99999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999799999999999999999979999999999999999999999999999999999999999999999999999999999999999999999999999999999919999999999499999999999999999999999999999999
#=GC scorecons_70         ******************************************************************************************************************************************************************************************************************_**********_********************************
#=GC scorecons_80         ***********************************************************************************************************_******************_***********************************************************************************_**********_********************************
#=GC scorecons_90         ***********************************************************************************************************_******************_***********************************************************************************_**********_********************************
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