# STOCKHOLM 1.0
#=GF ID 3.40.50.300/FF/339488
#=GF DE Formate hydrogenlyase transcriptional activator
#=GF AC 3.40.50.300/FF/339488
#=GF TP FunFam
#=GF DR CATH: 4.2
#=GF DR DOPS: 32.886
#=GS P71229/335-517      AC P71229
#=GS P71229/335-517      OS Escherichia coli K-12
#=GS P71229/335-517      DE DNA-binding transcriptional activator HyfR
#=GS P71229/335-517      DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS P71229/335-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS P71229/335-517      DR GO; GO:0003677; GO:0006352; GO:2000142; 
#=GS A0A127KZX9/306-490  AC A0A127KZX9
#=GS A0A127KZX9/306-490  OS Enterobacter sp. FY-07
#=GS A0A127KZX9/306-490  DE Formate hydrogen-lyase transcriptional activator
#=GS A0A127KZX9/306-490  DR GENE3D; 5b6a2cca9d9e15b90fddaba8119c83e3/306-490; 
#=GS A0A127KZX9/306-490  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Enterobacter; Enterobacter sp. FY-07; 
#=GS D8B9G6/335-517      AC D8B9G6
#=GS D8B9G6/335-517      OS Escherichia coli MS 175-1
#=GS D8B9G6/335-517      DE Sigma-54 interaction domain protein
#=GS D8B9G6/335-517      DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS D8B9G6/335-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS L3KHL9/335-517      AC L3KHL9
#=GS L3KHL9/335-517      OS Escherichia coli KTE51
#=GS L3KHL9/335-517      DE DNA-binding transcriptional activator, formate sensing
#=GS L3KHL9/335-517      DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS L3KHL9/335-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A0H3XAM9/335-517  AC A0A0H3XAM9
#=GS A0A0H3XAM9/335-517  OS Escherichia coli PCN061
#=GS A0A0H3XAM9/335-517  DE DNA-binding transcriptional activator, formate sensing
#=GS A0A0H3XAM9/335-517  DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS A0A0H3XAM9/335-517  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A142UZN5/335-517  AC A0A142UZN5
#=GS A0A142UZN5/335-517  OS Escherichia coli str. Sanji
#=GS A0A142UZN5/335-517  DE Hydrogenase
#=GS A0A142UZN5/335-517  DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS A0A142UZN5/335-517  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS F4SHT3/335-517      AC F4SHT3
#=GS F4SHT3/335-517      OS Escherichia coli H736
#=GS F4SHT3/335-517      DE Hydrogenase-4 transcriptional activator
#=GS F4SHT3/335-517      DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS F4SHT3/335-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS H9UV92/335-517      AC H9UV92
#=GS H9UV92/335-517      OS Escherichia coli P12b
#=GS H9UV92/335-517      DE Hydrogenase-4 transcriptional activator
#=GS H9UV92/335-517      DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS H9UV92/335-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A037YJ79/335-517  AC A0A037YJ79
#=GS A0A037YJ79/335-517  OS Escherichia coli
#=GS A0A037YJ79/335-517  DE DNA-binding transcriptional activator, formate sensing
#=GS A0A037YJ79/335-517  DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS A0A037YJ79/335-517  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS D8AW91/335-517      AC D8AW91
#=GS D8AW91/335-517      OS Escherichia coli MS 116-1
#=GS D8AW91/335-517      DE Sigma-54 interaction domain protein
#=GS D8AW91/335-517      DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS D8AW91/335-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A0E1M080/335-517  AC A0A0E1M080
#=GS A0A0E1M080/335-517  OS Escherichia coli 1303
#=GS A0A0E1M080/335-517  DE Hydrogenase-4 transcriptional activator
#=GS A0A0E1M080/335-517  DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS A0A0E1M080/335-517  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A070SQJ1/335-517  AC A0A070SQJ1
#=GS A0A070SQJ1/335-517  OS Escherichia coli 2-210-07_S3_C3
#=GS A0A070SQJ1/335-517  DE AAA domain family protein
#=GS A0A070SQJ1/335-517  DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS A0A070SQJ1/335-517  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS D8BWX2/335-517      AC D8BWX2
#=GS D8BWX2/335-517      OS Escherichia coli MS 196-1
#=GS D8BWX2/335-517      DE Sigma-54 interaction domain protein
#=GS D8BWX2/335-517      DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS D8BWX2/335-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A1J0HDY7/335-517  AC A0A1J0HDY7
#=GS A0A1J0HDY7/335-517  OS Escherichia coli str. K-12 substr. W3110
#=GS A0A1J0HDY7/335-517  DE Hydrogenase
#=GS A0A1J0HDY7/335-517  DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS A0A1J0HDY7/335-517  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A125X0N2/335-517  AC A0A125X0N2
#=GS A0A125X0N2/335-517  OS Escherichia coli 1-110-08_S3_C1
#=GS A0A125X0N2/335-517  DE AAA domain family protein
#=GS A0A125X0N2/335-517  DR GENE3D; 64c36310818379acae763dab37527c29/335-517; 
#=GS A0A125X0N2/335-517  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; 
#=GS A0A0H2V1A2/334-518  AC A0A0H2V1A2
#=GS A0A0H2V1A2/334-518  OS Shigella flexneri
#=GS A0A0H2V1A2/334-518  DE Formate hydrogen-lyase transcriptional activator for fdhF, hyc and hyp operons-like protein
#=GS A0A0H2V1A2/334-518  DR GENE3D; 01cc3c679a42cbd28988fe34bae54f39/334-518; 
#=GS A0A0H2V1A2/334-518  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella; Shigella flexneri; 
#=GS E7TDR3/195-376      AC E7TDR3
#=GS E7TDR3/195-376      OS Shigella flexneri CDC 796-83
#=GS E7TDR3/195-376      DE Formate hydrogenlyase transcriptional activator
#=GS E7TDR3/195-376      DR GENE3D; 284ec643cb8d3203b022b5383d7dd2b1/195-376; 
#=GS E7TDR3/195-376      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella; Shigella flexneri; 
#=GS A0A1C4FJS8/309-494  AC A0A1C4FJS8
#=GS A0A1C4FJS8/309-494  OS Kosakonia oryziphila
#=GS A0A1C4FJS8/309-494  DE Hydrogenase-4 transcriptional activator
#=GS A0A1C4FJS8/309-494  DR GENE3D; 621b519978e2fe98312c10fb8904f0e0/309-494; 
#=GS A0A1C4FJS8/309-494  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Kosakonia; Kosakonia oryziphila; 
#=GS R9VK61/309-494      AC R9VK61
#=GS R9VK61/309-494      OS Enterobacter sp. R4-368
#=GS R9VK61/309-494      DE Hydrogenase
#=GS R9VK61/309-494      DR GENE3D; 6f33194b7b235c1fcfe7d3be8c0ff95e/309-494; 
#=GS R9VK61/309-494      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Enterobacter; Enterobacter sp. R4-368; 
#=GS B7LKF0/333-517      AC B7LKF0
#=GS B7LKF0/333-517      OS Escherichia fergusonii ATCC 35469
#=GS B7LKF0/333-517      DE Hydrogenase-4 transcriptional activator
#=GS B7LKF0/333-517      DR GENE3D; b1d2dace92941176f04a6f96cddaba01/333-517; 
#=GS B7LKF0/333-517      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia fergusonii; 
#=GS A0A0G3Q873/310-494  AC A0A0G3Q873
#=GS A0A0G3Q873/310-494  OS Kluyvera intermedia
#=GS A0A0G3Q873/310-494  DE Hydrogenase
#=GS A0A0G3Q873/310-494  DR GENE3D; acc5fd71a524c3cb63e0e22f90cfb579/310-494; 
#=GS A0A0G3Q873/310-494  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Kluyvera; Kluyvera intermedia; 
#=GS E7SGS1/193-350      AC E7SGS1
#=GS E7SGS1/193-350      OS Shigella dysenteriae CDC 74-1112
#=GS E7SGS1/193-350      DE Formate hydrogenlyase transcriptional activator
#=GS E7SGS1/193-350      DR GENE3D; fe5a88ac8dfcbd44ec1aee739d975acd/193-350; 
#=GS E7SGS1/193-350      DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella; Shigella dysenteriae; 
#=GF TC 297.1 3.0E-92
#=GF SQ 22
P71229/335-517              ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A127KZX9/306-490          -KLNEQIFSSQSFGDIIYQSDAMRDVLQQVNIVALSDSTVLILGETGTGKEIIARALHQMSPRKDKPLVKINCAAIPASLLESELFGHDKGAFTGAINAHRGRFEMADEGTLFLDEIGDMPLELQPKLLRVLQEREIERIGGTRTIPVNVRVIAATNRDLRQMVIDREFRNDLFYRLNVFPLVLPP
D8B9G6/335-517              ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
L3KHL9/335-517              ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A0H3XAM9/335-517          ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A142UZN5/335-517          ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
F4SHT3/335-517              ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
H9UV92/335-517              ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A037YJ79/335-517          ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
D8AW91/335-517              ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A0E1M080/335-517          ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A070SQJ1/335-517          ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
D8BWX2/335-517              ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A1J0HDY7/335-517          ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A125X0N2/335-517          ---SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A0H2V1A2/334-518          -QLSEQLLSNLGVGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRHDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
E7TDR3/195-376              ----EQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARALHQLSTRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSNLFYRLNVFPLELPP
A0A1C4FJS8/309-494          RQLNEQIASSQSFGDIIYQSDAMRDVLQQVNIVALSDSTVLILGETGTGKEIIARALHQMSPRKDKPLVKINCAAIPSSLLESELFGHDKGAFTGAINTHRGRFEMADEGTLFLDEIGDMPLELQPKLLRVLQEREIERIGGNRTIPVNVRVIAATNRDLRQMVIDREFRNDLFYRLNVFPLVLPP
R9VK61/309-494              RKLNEQIASSQSLGDIIYQSDAMRDVLQQVNIVALSDSTVLILGETGTGKEIIARALHQMSPRKDKPLVKINCAAIPASLLESELFGHDKGAFTGAINAHRGRFEMADEGTLFLDEIGDMPLELQPKLLRVLQEREIERIGGTKTIPVNVRVIAATNRDLRQMVIDREFRNDLFYRLNVFPLVLPP
B7LKF0/333-517              -QLNEQLHCSQHVGDIIYQSQVMEELLQQVGIVAQSDSTVLLCGETGTGKEVIARTIHQLSLRHDKPLVKINCAAIPAALLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEKEIERLGGNRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPP
A0A0G3Q873/310-494          -KLNEQILSSQSFGDIIYQSDAMRDVLQQVNIVALSDSTVLILGETGTGKEIIARAIHQMSLRKDKPLVKINCAAIPSTLLESELFGHDKGAFTGAINAHRGRFEMADGGTLFLDEIGDMPIELQPKLLRVLQEREIERIGGTRTIPVNVRVIAATNRDLKQMVIDREFRNDLFYRLNVFPLVLPP
E7SGS1/193-350              --LSEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSAVLICGETGTGKEVIARAIHQLSTRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGMLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDL--------------------------
#=GC scorecons              012599658655599999996896869999699949997998599999999799986996959699999999999997799999999999999999997999999699697999999996989999999999998999969958999999999999999946663664664666666666663666
#=GC scorecons_70           ____***_*____*******_**_******_***_*******_******************_********************************************************************************_*****************_***_**_**_***********_***
#=GC scorecons_80           ____**__*____*******_**_*_****_***_*******_*************_**_*_*_**********************************_******_**_**********_*******************_**_*****************__________________________
#=GC scorecons_90           ____**__*____*******_**_*_****_***_***_***_********_****_**_*_*_*************__*******************_******_**_*_********_*******************_**_*****************__________________________
//