# STOCKHOLM 1.0
#=GF ID 1.10.3280.10/FF/97
#=GF DE Siroheme biosynthesis protein met8
#=GF AC 1.10.3280.10/FF/97
#=GF TP FunFam
#=GF DR CATH: 4.2
#=GF DR DOPS: 66.674
#=GS 1kyqA03/190-274     AC P15807
#=GS 1kyqA03/190-274     OS Saccharomyces cerevisiae S288C
#=GS 1kyqA03/190-274     DE Siroheme biosynthesis protein MET8
#=GS 1kyqA03/190-274     DR CATH; 1kyq; A:190-273; 
#=GS 1kyqA03/190-274     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 1kyqA03/190-274     DR GO; GO:0000103; GO:0004325; GO:0019354; GO:0043115; 
#=GS 1kyqA03/190-274     DR EC; 1.3.1.76; 4.99.1.4; 
#=GS 1kyqB03/190-274     AC P15807
#=GS 1kyqB03/190-274     OS Saccharomyces cerevisiae S288C
#=GS 1kyqB03/190-274     DE Siroheme biosynthesis protein MET8
#=GS 1kyqB03/190-274     DR CATH; 1kyq; B:190-273; 
#=GS 1kyqB03/190-274     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 1kyqB03/190-274     DR GO; GO:0000103; GO:0004325; GO:0019354; GO:0043115; 
#=GS 1kyqB03/190-274     DR EC; 1.3.1.76; 4.99.1.4; 
#=GS 1kyqC03/189-274     AC P15807
#=GS 1kyqC03/189-274     OS Saccharomyces cerevisiae S288C
#=GS 1kyqC03/189-274     DE Siroheme biosynthesis protein MET8
#=GS 1kyqC03/189-274     DR CATH; 1kyq; C:189-273; 
#=GS 1kyqC03/189-274     DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS 1kyqC03/189-274     DR GO; GO:0000103; GO:0004325; GO:0019354; GO:0043115; 
#=GS 1kyqC03/189-274     DR EC; 1.3.1.76; 4.99.1.4; 
#=GS O14172/163-243      AC O14172
#=GS O14172/163-243      OS Schizosaccharomyces pombe 972h-
#=GS O14172/163-243      DE Siroheme biosynthesis protein met8
#=GS O14172/163-243      DR GENE3D; a7debbee792e5283c55ed5e7d4d16c8d/163-243; 
#=GS O14172/163-243      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; Schizosaccharomyces pombe; 
#=GS O14172/163-243      DR GO; GO:0000103; GO:0004325; GO:0005634; GO:0005829; GO:0019354; GO:0043115; 
#=GS O14172/163-243      DR EC; 1.3.1.76; 4.99.1.4; 
#=GS P15807/190-274      AC P15807
#=GS P15807/190-274      OS Saccharomyces cerevisiae S288C
#=GS P15807/190-274      DE Siroheme biosynthesis protein MET8
#=GS P15807/190-274      DR GENE3D; 8afd3fb595180185747f277f3ffa1219/190-274; 
#=GS P15807/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS P15807/190-274      DR GO; GO:0000103; GO:0004325; GO:0019354; GO:0043115; 
#=GS P15807/190-274      DR EC; 1.3.1.76; 4.99.1.4; 
#=GS A6ZLF3/190-274      AC A6ZLF3
#=GS A6ZLF3/190-274      OS Saccharomyces cerevisiae YJM789
#=GS A6ZLF3/190-274      DE Methionine requiring protein
#=GS A6ZLF3/190-274      DR GENE3D; 29a8b87b7766d1d6c00c6fe8dcc5f4e6/190-274; 
#=GS A6ZLF3/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E7NF26/190-274      AC E7NF26
#=GS E7NF26/190-274      OS Saccharomyces cerevisiae FostersO
#=GS E7NF26/190-274      DE Met8p
#=GS E7NF26/190-274      DR GENE3D; 393e5aa22f7706cdd848c6f402e9d21b/190-274; 
#=GS E7NF26/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS N1PAV2/190-274      AC N1PAV2
#=GS N1PAV2/190-274      OS Saccharomyces cerevisiae CEN.PK113-7D
#=GS N1PAV2/190-274      DE Met8p
#=GS N1PAV2/190-274      DR GENE3D; 393e5aa22f7706cdd848c6f402e9d21b/190-274; 
#=GS N1PAV2/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS H0GRJ0/188-272      AC H0GRJ0
#=GS H0GRJ0/188-272      OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7
#=GS H0GRJ0/188-272      DE Met8p
#=GS H0GRJ0/188-272      DR GENE3D; 3cf94d48524d469631c3da09fc7e7768/188-272; 
#=GS H0GRJ0/188-272      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; 
#=GS J8PRC4/190-274      AC J8PRC4
#=GS J8PRC4/190-274      OS Saccharomyces arboricola H-6
#=GS J8PRC4/190-274      DE Met8p
#=GS J8PRC4/190-274      DR GENE3D; 4173f5569e2422ee2b3cc3cf9191cb19/190-274; 
#=GS J8PRC4/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces arboricola; 
#=GS E7K9I0/80-164       AC E7K9I0
#=GS E7K9I0/80-164       OS Saccharomyces cerevisiae AWRI796
#=GS E7K9I0/80-164       DE Met8p
#=GS E7K9I0/80-164       DR GENE3D; 65953944edbff21800fe268a5bf62cf2/80-164; 
#=GS E7K9I0/80-164       DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS J4U4K2/190-274      AC J4U4K2
#=GS J4U4K2/190-274      OS Saccharomyces kudriavzevii IFO 1802
#=GS J4U4K2/190-274      DE MET8-like protein
#=GS J4U4K2/190-274      DR GENE3D; 75a1081ad699f8d141d8b82b6b448a0a/190-274; 
#=GS J4U4K2/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces kudriavzevii; 
#=GS G2W9L6/190-274      AC G2W9L6
#=GS G2W9L6/190-274      OS Saccharomyces cerevisiae Kyokai no. 7
#=GS G2W9L6/190-274      DE K7_Met8p
#=GS G2W9L6/190-274      DR GENE3D; 84e7e55e9de4355453cfcbced412da53/190-274; 
#=GS G2W9L6/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS H0GCR4/190-274      AC H0GCR4
#=GS H0GCR4/190-274      OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7
#=GS H0GCR4/190-274      DE Met8p
#=GS H0GCR4/190-274      DR GENE3D; 8d8d846b0d08ea4da31eff4e7bf304f7/190-274; 
#=GS H0GCR4/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; 
#=GS E7KKK7/190-274      AC E7KKK7
#=GS E7KKK7/190-274      OS Saccharomyces cerevisiae Lalvin QA23
#=GS E7KKK7/190-274      DE Met8p
#=GS E7KKK7/190-274      DR GENE3D; 8d8d846b0d08ea4da31eff4e7bf304f7/190-274; 
#=GS E7KKK7/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS C7GUY5/190-274      AC C7GUY5
#=GS C7GUY5/190-274      OS Saccharomyces cerevisiae JAY291
#=GS C7GUY5/190-274      DE Met8p
#=GS C7GUY5/190-274      DR GENE3D; acd4a79be9637d2d2cf98a5cba024de8/190-274; 
#=GS C7GUY5/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A0A0L8VVF8/190-274  AC A0A0L8VVF8
#=GS A0A0L8VVF8/190-274  OS Saccharomyces sp. 'boulardii'
#=GS A0A0L8VVF8/190-274  DE MET8p Bifunctional dehydrogenase and ferrochelatase
#=GS A0A0L8VVF8/190-274  DR GENE3D; acd4a79be9637d2d2cf98a5cba024de8/190-274; 
#=GS A0A0L8VVF8/190-274  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; 
#=GS E7QBN6/190-274      AC E7QBN6
#=GS E7QBN6/190-274      OS Saccharomyces cerevisiae VL3
#=GS E7QBN6/190-274      DE Met8p
#=GS E7QBN6/190-274      DR GENE3D; acd4a79be9637d2d2cf98a5cba024de8/190-274; 
#=GS E7QBN6/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E7LRF2/190-274      AC E7LRF2
#=GS E7LRF2/190-274      OS Saccharomyces cerevisiae Vin13
#=GS E7LRF2/190-274      DE Met8p
#=GS E7LRF2/190-274      DR GENE3D; acd4a79be9637d2d2cf98a5cba024de8/190-274; 
#=GS E7LRF2/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A0SXL1/190-274      AC A0SXL1
#=GS A0SXL1/190-274      OS Saccharomyces cerevisiae
#=GS A0SXL1/190-274      DE Bifunctional dehydrogenase/ferrochelatase
#=GS A0SXL1/190-274      DR GENE3D; acd4a79be9637d2d2cf98a5cba024de8/190-274; 
#=GS A0SXL1/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS D3UEV9/190-274      AC D3UEV9
#=GS D3UEV9/190-274      OS Saccharomyces cerevisiae EC1118
#=GS D3UEV9/190-274      DE Met8p
#=GS D3UEV9/190-274      DR GENE3D; acd4a79be9637d2d2cf98a5cba024de8/190-274; 
#=GS D3UEV9/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B3LMU7/190-274      AC B3LMU7
#=GS B3LMU7/190-274      OS Saccharomyces cerevisiae RM11-1a
#=GS B3LMU7/190-274      DE Siroheme biosynthesis protein MET8
#=GS B3LMU7/190-274      DR GENE3D; b62bf635d0d6861093672bb241c16889/190-274; 
#=GS B3LMU7/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A0A0L8RM43/190-274  AC A0A0L8RM43
#=GS A0A0L8RM43/190-274  OS Saccharomyces eubayanus
#=GS A0A0L8RM43/190-274  DE MET8-like protein
#=GS A0A0L8RM43/190-274  DR GENE3D; df3101ab80ba7f10fb983f5a74d2e418/190-274; 
#=GS A0A0L8RM43/190-274  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces eubayanus; 
#=GS E7Q183/190-274      AC E7Q183
#=GS E7Q183/190-274      OS Saccharomyces cerevisiae FostersB
#=GS E7Q183/190-274      DE Met8p
#=GS E7Q183/190-274      DR GENE3D; ea7bc1e3612fb777d33bc31a9b0bb567/190-274; 
#=GS E7Q183/190-274      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GF TC 95.0 1.7E-30
#=GF SQ 24
1kyqA03/190-274             -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRXDWARRCTDLFGIQHCHNID---VKRLLDLFKVXFQEQNCSLQFPPRERLLSEYCSS
1kyqB03/190-274             -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRXDWARRCTDLFGIQHCHNID---VKRLLDLFKVXFQEQNCSLQFPPRERLLSEYCSS
1kyqC03/189-274             GDLALEDAVVKLGELRRGIRLLAPDDKDVKYRXDWARRCTDLFGIQHCHNID---VKRLLDLFKVXFQEQNCSLQFPPRERLLSEYCSS
O14172/163-243              ---ATGMALEKTGLLRQKLRDIVPEPENSRKRMRWMIEICELWSLEELAMLDENLINRLLGYFPKK-TPSYREITTPAYSKIDNY----
P15807/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
A6ZLF3/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
E7NF26/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
N1PAV2/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
H0GRJ0/188-272              -DLALEDAVVKLGELRRGIRLLAPNDKDVKYRMDWAKRCTDLFGIQHCHDID---VERLLKLFKTMFHDQNCSLQFPSKERLLRDYCSS
J8PRC4/190-274              -DLALEDAVVKLGELRSGIRLLAPDDKDVKYRMSWAKRCTDLFGIQHCHNID---VERLLGLFKTMFKDQNCSLQFPPKEQLHSDYCSS
E7K9I0/80-164               -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
J4U4K2/190-274              -DLALEDAVVKLGELRRGIRLLAPNDKDVKYRMDWAKRCTDLFGIQHCHDID---VERLLGLFKTMFHDQNCSLQFPSKERLLRDYCSS
G2W9L6/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
H0GCR4/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
E7KKK7/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
C7GUY5/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
A0A0L8VVF8/190-274          -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
E7QBN6/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
E7LRF2/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
A0SXL1/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
D3UEV9/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
B3LMU7/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
A0A0L8RM43/190-274          -DLALEDAVVKLGELRRGIRLLAPNDKDVKYRMDWAKRCTDLFGIQHCHEID---VQRLLGLFKTMLQEQHRSLQFPPRDQMLSYYCSS
E7Q183/190-274              -DLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNID---VKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
#=GC scorecons              04495659659594996569466965665759759546557956666554690007599955953444455556559545664544444
#=GC scorecons_70           ___*_*_**_*_*_**__**_***__**_*_**_*_____**_***____**___*_***__*__________*__*___**_______
#=GC scorecons_80           ___*___*__*_*_**___*___*_____*_*__*_____**_________*___*_***__*_____________*____________
#=GC scorecons_90           ___*___*__*_*_**___*___*_______*__*______*_________*_____***__*_____________*____________
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