View in Gene3D

CATH Superfamily 3.30.160.510

Histone-like nucleoid-structuring protein H-NS

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Histone-like nucleoid-structuring protein H-NS
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Histone-like nucleoid-structuring protein H-NS

Tis superfamily entry represents the histone-like nucleoid-structuring (H-NS) protein, a DNA-binding protein implicated in transcriptional repression (silencing) as well as in bacterial chromosome organisation PMID:7875316. H-NS binds tightly to AT-rich dsDNA, increases its thermal stability and inhibits transcription. It also binds to ssDNA and RNA but with a much lower affinity PMID:18387844.

INTERPRO:IPR001801,PFAM:PF00816

GO Diversity

Unique GO annotations
0 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
160 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO:
Taxonomy
Unique Species: 160
CATH-Gene3D is a Global Biodata Core Resource Learn more...