CATH Domain 5n4sA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family	Class B metallo-beta-lactamase

Enzyme Information

UniProtKB Entries (1)

Q9K2N0_PSEAI

Pseudomonas aeruginosa

Beta-lactamase class B VIM-2

PDB Structure

PDB	5N4S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-beta-lactamase inhibition. Li, G.B., Brem, J., Lesniak, R., Abboud, M.I., Lohans, C.T., Clifton, I.J., Yang, S.Y., Jimenez-Castellanos, J.C., Avison, M.B., Spencer, J., McDonough, M.A., Schofield, C.J. Chem. Commun. (Camb.)