CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Aminopeptidase, subunit E, domain 1
Functional Family M17 leucyl aminopeptidase

Enzyme Information

UniProtKB Entries (1)

A0A024V0B1
A0A024V0B1_PLAFA
Plasmodium falciparum Vietnam Oak-Knoll (FVO)
Uncharacterized protein

PDB Structure

PDB 4ZYQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J.
Eur.J.Med.Chem.