CATH Domain 4elfA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family	Dihydrofolate reductase

Enzyme Information

UniProtKB Entries (1)

Q81R22_BACAN

Bacillus anthracis

Dihydrofolate reductase

PDB Structure

PDB	4ELF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase. Bourne, C.R., Wakeham, N., Nammalwar, B., Tseitin, V., Bourne, P.C., Barrow, E.W., Mylvaganam, S., Ramnarayan, K., Bunce, R.A., Berlin, K.D., Barrow, W.W. Biochim.Biophys.Acta