CATH Classification

Domain Context

CATH Clusters

Superfamily Pancreatic trypsin inhibitor Kunitz domain
Functional Family Pancreatic trypsin inhibitor

Enzyme Information

UniProtKB Entries (2)

P00974
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor
P35030
TRY3_HUMAN
Homo sapiens
Trypsin-3

PDB Structure

PDB 3P95
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The P2' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.
Salameh, M.A., Soares, A.S., Hockla, A., Radisky, D.C., Radisky, E.S.
Biochem.J.
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