CATH Domain 3kxuA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1260	Ferritin
	1.20.1260.10	Ferritin, core subunit, four-helix bundle

Domain Context

CATH Clusters

Superfamily	1.20.1260.10
Functional Family	Ferritin light chain

Enzyme Information

UniProtKB Entries (1)

FRIL_HUMAN

Homo sapiens

Ferritin light chain

PDB Structure

PDB	3KXU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. Luscieti, S., Santambrogio, P., Langlois d'Estaintot, B., Granier, T., Cozzi, A., Poli, M., Gallois, B., Finazzi, D., Cattaneo, A., Levi, S., Arosio, P. J.Biol.Chem.