CATH Domain 3ek8A02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.155	Green Fluorescent Protein
	2.40.155.10	Green fluorescent protein

Domain Context

CATH Clusters

Superfamily	Green fluorescent protein
Functional Family

Enzyme Information

2.7.11.18

[Myosin light-chain] kinase.

based on mapping to UniProt P11799

ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate.

-!- Requires calmodulin for activity. -!- The 20 kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, more slowly. -!- Formerly EC 2.7.1.117.

UniProtKB Entries (3)

P0DP29	CALM1_RAT Rattus norvegicus Calmodulin-1
P11799	MYLK_CHICK Gallus gallus Myosin light chain kinase, smooth muscle
P42212	GFP_AEQVI Aequorea victoria Green fluorescent protein

PDB Structure

PDB	3EK8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design Akerboom, J., Rivera, J.D., Guilbe, M.M., Malave, E.C., Hernandez, H.H., Tian, L., Hires, S.A., Marvin, J.S., Looger, L.L., Schreiter, E.R. J.Biol.Chem.