CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.20 | 5' to 3' exonuclease, C-terminal subdomain |
Domain Context
CATH Clusters
| Superfamily | 5' to 3' exonuclease, C-terminal subdomain |
| Functional Family | DNA repair endonuclease XPF isoform X2 |
Enzyme Information
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt Q92889
|
UniProtKB Entries (1)
| P07992 |
ERCC1_HUMAN
Homo sapiens
DNA excision repair protein ERCC-1
|
PDB Structure
| PDB | 2MUT |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex.
J.Biol.Chem.
|
