CATH Classification

Domain Context

CATH Clusters

Superfamily Protein-arginine deiminase, N-terminal domain
Functional Family Protein-arginine deiminase type-4

Enzyme Information

3.5.3.15
Protein-arginine deiminase.
based on mapping to UniProt Q9UM07
Protein L-arginine + H(2)O = protein L-citrulline + NH(3).
-!- Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.

UniProtKB Entries (1)

Q9UM07
PADI4_HUMAN
Homo sapiens
Protein-arginine deiminase type-4

PDB Structure

PDB 2DW5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization
Luo, Y., Arita, K., Bhatia, M., Knuckley, B., Lee, Y.H., Stallcup, M.R., Sato, M., Thompson, P.R.
Biochemistry
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