CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt O59952
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (1)

O59952
LIP_THELA
Thermomyces lanuginosus
Lipase

PDB Structure

PDB 1TIB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
Derewenda, U., Swenson, L., Wei, Y., Green, R., Kobos, P.M., Joerger, R., Haas, M.J., Derewenda, Z.S.
J.Lipid Res.
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