CATH Domain 1mfwA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.230	Doublecortin domain

Domain Context

CATH Clusters

Superfamily	Doublecortin domain
Functional Family	serine/threonine-protein kinase DCLK1 isoform X1

Enzyme Information

2.7.11.1

Non-specific serine/threonine protein kinase.

based on mapping to UniProt O15075

ATP + a protein = ADP + a phosphoprotein.

-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O15075

DCLK1_HUMAN

Homo sapiens

Serine/threonine-protein kinase DCLK1

PDB Structure

PDB	1MFW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase Kim, M.H., Cierpickil, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z. Nat.Struct.Biol.