CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Complement factor D

Enzyme Information

3.4.21.20
Cathepsin G.
based on mapping to UniProt P08311
Specificity similar to chymotrypsin C.
-!- From azurophil granules of polymorphonuclear leukocytes. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P08311
CATG_HUMAN
Homo sapiens
Cathepsin G

PDB Structure

PDB 1KYN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design.
Greco, M.N., Hawkins, M.J., Powell, E.T., Almond Jr., H.R., Corcoran, T.W., de Garavilla, L., Kauffman, J.A., Recacha, R., Chattopadhyay, D., Andrade-Gordon, P., Maryanoff, B.E.
J.Am.Chem.Soc.
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