CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.50 | 3-Layer(bba) Sandwich | |
3.50.50 | FAD/NAD(P)-binding domain | |
3.50.50.60 | FAD/NAD(P)-binding domain |
Domain Context
CATH Clusters
Superfamily | FAD/NAD(P)-binding domain |
Functional Family | Thioredoxin reductase 1, cytoplasmic |
Enzyme Information
1.8.1.9 |
Thioredoxin-disulfide reductase.
based on mapping to UniProt O89049
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.
|
UniProtKB Entries (1)
O89049 |
TRXR1_RAT
Rattus norvegicus
Thioredoxin reductase 1, cytoplasmic
|
PDB Structure
PDB | 1H6V |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Three-Dimensional Structure of a Mammalian Thioredoxin Reductase: Implication for Mechanism and Evolution of a Selenocysteine Dependent Enzyme
Proc.Natl.Acad.Sci.USA
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