CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1490 | Dna Ligase; domain 1 |
|
3.30.1490.20 | ATP-grasp fold, A domain |
Domain Context
CATH Clusters
| Superfamily | ATP-grasp fold, A domain |
| Functional Family | Glutathione synthetase |
Enzyme Information
| 6.3.2.3 |
Glutathione synthase.
based on mapping to UniProt P04425
ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione.
|
UniProtKB Entries (1)
| P04425 |
GSHB_ECOLI
Escherichia coli K-12
Glutathione synthetase
|
PDB Structure
| PDB | 1GSA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
A pseudo-michaelis quaternary complex in the reverse reaction of a ligase: structure of Escherichia coli B glutathione synthetase complexed with ADP, glutathione, and sulfate at 2.0 A resolution.
Biochemistry
|
