PDB 4zy0

PDB Information

PDB4ZY0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum FcB1/Columbia
Primary Citation
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J.
Eur.J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-21
Resolution2.200
CATH Insert Date10 Apr, 2016

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped
E 11 Apr, 2016 Chopped
F 11 Apr, 2016 Chopped
G 11 Apr, 2016 Chopped
H 11 Apr, 2016 Chopped
I 11 Apr, 2016 Chopped
J 11 Apr, 2016 Chopped
K 11 Apr, 2016 Chopped
L 11 Apr, 2016 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4zy0A01 03 May, 2016 3.40.220.10 Assigned
4zy0A02 03 May, 2016 3.40.630.10 Assigned
4zy0B01 03 May, 2016 3.40.220.10 Assigned
4zy0B02 03 May, 2016 3.40.630.10 Assigned
4zy0C01 03 May, 2016 3.40.220.10 Assigned
4zy0C02 03 May, 2016 3.40.630.10 Assigned
4zy0D01 03 May, 2016 3.40.220.10 Assigned
4zy0D02 03 May, 2016 3.40.630.10 Assigned
4zy0E01 03 May, 2016 3.40.220.10 Assigned
4zy0E02 03 May, 2016 3.40.630.10 Assigned
4zy0F01 03 May, 2016 3.40.220.10 Assigned
4zy0F02 03 May, 2016 3.40.630.10 Assigned
4zy0G01 03 May, 2016 3.40.220.10 Assigned
4zy0G02 03 May, 2016 3.40.630.10 Assigned
4zy0H01 03 May, 2016 3.40.220.10 Assigned
4zy0H02 03 May, 2016 3.40.630.10 Assigned
4zy0I01 03 May, 2016 3.40.220.10 Assigned
4zy0I02 03 May, 2016 3.40.630.10 Assigned
4zy0J01 03 May, 2016 3.40.220.10 Assigned
4zy0J02 03 May, 2016 3.40.630.10 Assigned
4zy0K01 03 May, 2016 3.40.220.10 Assigned
4zy0K02 03 May, 2016 3.40.630.10 Assigned
4zy0L01 03 May, 2016 3.40.220.10 Assigned
4zy0L02 03 May, 2016 3.40.630.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein