PDB 2p8h

PDB Information

PDB2P8H
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1.
Barrow, J.C., Rittle, K.E., Ngo, P.L., Selnick, H.G., Graham, S.L., Pitzenberger, S.M., McGaughey, G.B., Colussi, D., Lai, M.T., Huang, Q., Tugusheva, K., Espeseth, A.S., Simon, A.J., Munshi, S.K., Vacca, J.P.
Chemmedchem
HeaderHydrolase
Released2007-03-22
Resolution1.800
CATH Insert Date07 Nov, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2p8hA01 23 Nov, 2007 2.40.70.10 Assigned
2p8hA02 23 Nov, 2007 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1